Dynamic small bowel MRI scan
Manual assessment is possible but time consuming and we have developed registration technology called GIQuant to help speed up and automate motility assessment. GIQuant is used in single regions of interest to inspect inflammatory lesions in Crohn’s disease where low motility is often a sign of disease.
Normal motile terminal ileum in IBD subject
Abnormal motile terminal ileum in IBD subject
Regional & Global assessment
GIQuant can also be used to assess global or segmental bowel motility. In the color-plots below we can see high and low motility at the terminal ileum corresponding to the motility series above. Global assessment in conditions like diabetic neuropathy, pseudo-obstruction or Hirschprung’s can be assessed by placing a region of interest across the whole bowel.
Motility map depicting good motility at the terminal ileum (corresponding to motility series above)
Motility map depicting low motility at the terminal ileum (corresponding to motility series above)
Using a combination of image registration and insights from conventional high-resolution manometry, spatio-temporal mapping of the GI tract can be performed to provide detail on how the bowel is contracting.
Semi-automated spatio-temporal mapping technique used in the stomach
Spatio-temporal map of gastric motility
Supporting robust research
MRI and GIQuant is being used in a growing number of studies to explore dysmotility in both health and disease. It is our hope that insights from MRI will soon be pared with clinical treatment strategies and are committed to supporting research in this area. Please do not hesitate to get in touch to find out more.